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Deletion of Mettl3 at the Pro-B Stage Marginally Affects B Cell Development and Profibrogenic Activity of B Cells in Liver Fibrosis

N6-methyladenosine (m(6)A) modification plays a pivotal role in cell fate determination. Previous studies show that eliminating m(6)A using Mb1-Cre dramatically impairs B cell development. However, whether disturbing m(6)A modification at later stages affects B cell development and function remains...

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Detalles Bibliográficos
Autores principales: Kang, Xinmei, Chen, Shuhan, Pan, Lijie, Liang, Xiaoqi, Lu, Di, Chen, Huaxin, Li, Yanli, Liu, Chang, Ge, Mian, Zhang, Qi, Liu, Qiuli, Xu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213183/
https://www.ncbi.nlm.nih.gov/pubmed/35747688
http://dx.doi.org/10.1155/2022/8118577