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NMDA receptor inhibition prevents intracellular sodium elevations in human olfactory neuroepithelial precursors derived from bipolar patients
Dysregulation of ion flux across membranes and glutamate-induced excitotoxicity appear to be important pathophysiologic abnormalities in bipolar illness. Understanding ion control and responses to ionic stress is important to decipher the pathogenesis of this disorder. Monensin alone significantly i...
Autores principales: | Gao, Yonglin, Mack, Aaron A., Litteral, Carleigh, Delamere, Nicholas A., El-Mallakh, Rif S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213398/ https://www.ncbi.nlm.nih.gov/pubmed/35729322 http://dx.doi.org/10.1038/s41598-022-14187-w |
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