A scalable, open-source implementation of a large-scale mechanistic model for single cell proliferation and death signaling

Mechanistic models of how single cells respond to different perturbations can help integrate disparate big data sets or predict response to varied drug combinations. However, the construction and simulation of such models have proved challenging. Here, we developed a python-based model creation and...

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Detalles Bibliográficos
Autores principales: Erdem, Cemal, Mutsuddy, Arnab, Bensman, Ethan M., Dodd, William B., Saint-Antoine, Michael M., Bouhaddou, Mehdi, Blake, Robert C., Gross, Sean M., Heiser, Laura M., Feltus, F. Alex, Birtwistle, Marc R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213456/
https://www.ncbi.nlm.nih.gov/pubmed/35729113
http://dx.doi.org/10.1038/s41467-022-31138-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213456/
https://www.ncbi.nlm.nih.gov/pubmed/35729113
http://dx.doi.org/10.1038/s41467-022-31138-1

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