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A scalable, open-source implementation of a large-scale mechanistic model for single cell proliferation and death signaling
Mechanistic models of how single cells respond to different perturbations can help integrate disparate big data sets or predict response to varied drug combinations. However, the construction and simulation of such models have proved challenging. Here, we developed a python-based model creation and...
Autores principales: | Erdem, Cemal, Mutsuddy, Arnab, Bensman, Ethan M., Dodd, William B., Saint-Antoine, Michael M., Bouhaddou, Mehdi, Blake, Robert C., Gross, Sean M., Heiser, Laura M., Feltus, F. Alex, Birtwistle, Marc R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213456/ https://www.ncbi.nlm.nih.gov/pubmed/35729113 http://dx.doi.org/10.1038/s41467-022-31138-1 |
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