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Integrating chromatin accessibility states in the design of targeted sequencing panels for liquid biopsy

Dying tumor cells shed DNA fragments into the circulation that are known as circulating tumor DNA (ctDNA). Liquid biopsy tests aim to detect cancer using known markers, including genetic alterations and epigenetic profiles of ctDNA. Despite various advantages, the major limitation remains the low fr...

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Detalles Bibliográficos
Autores principales: Taklifi, Pegah, Palizban, Fahimeh, Mehrmohamadi, Mahya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213477/
https://www.ncbi.nlm.nih.gov/pubmed/35729208
http://dx.doi.org/10.1038/s41598-022-14675-z