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Integrating chromatin accessibility states in the design of targeted sequencing panels for liquid biopsy
Dying tumor cells shed DNA fragments into the circulation that are known as circulating tumor DNA (ctDNA). Liquid biopsy tests aim to detect cancer using known markers, including genetic alterations and epigenetic profiles of ctDNA. Despite various advantages, the major limitation remains the low fr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213477/ https://www.ncbi.nlm.nih.gov/pubmed/35729208 http://dx.doi.org/10.1038/s41598-022-14675-z |