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Studies on the antiviral activity of chebulinic acid against dengue and chikungunya viruses and in silico investigation of its mechanism of inhibition

Chebulinic acid (CA), originally isolated from the flower extract of the plant Terminalia chebula, has been shown to inhibit infection of herpes simplex virus-2 (HSV-2), suggestively by inhibiting the host entry step of viral infection. Like HSV-2, the dengue virus (DENV) and chikungunya virus (CHIK...

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Detalles Bibliográficos
Autores principales: Thomas, Naiju, Patil, Poonam, Sharma, Anjana, Kumar, Sandeep, Singh, Vikas Kumar, Alagarasu, Kalichamy, Parashar, Deepti, Tapryal, Suman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213501/
https://www.ncbi.nlm.nih.gov/pubmed/35729191
http://dx.doi.org/10.1038/s41598-022-13923-6