CD73 downregulation by EGFR-targeted liposomal CD73 siRNA potentiates antitumor effect of liposomal doxorubicin in 4T1 tumor-bearing mice

Blocking CD73 ectonucleotidase has been proposed as a potential therapeutic approach for cancer treatment. The present study aimed to investigate the antitumor effect of a novel EGFR-Targeted liposomal CD73 siRNA formulation in combination therapy with liposomal doxorubicin in the 4T1 mouse model. C...

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Detalles Bibliográficos
Autores principales: Soleimani, Anvar, Mirzavi, Farshad, Nikoofal-Sahlabadi, Sara, Nikpoor, Amin Reza, Taghizadeh, Bita, Barati, Mehdi, Soukhtanloo, Mohammad, Jaafari, Mahmoud Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213518/
https://www.ncbi.nlm.nih.gov/pubmed/35729230
http://dx.doi.org/10.1038/s41598-022-14392-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213518/
https://www.ncbi.nlm.nih.gov/pubmed/35729230
http://dx.doi.org/10.1038/s41598-022-14392-7

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