Efficient terminal erythroid differentiation requires the APC/C cofactor Cdh1 to limit replicative stress in erythroblasts

The APC/C-Cdh1 ubiquitin ligase complex drives proteosomal degradation of cell cycle regulators and other cellular proteins during the G1 phase of the cycle. The complex serves as an important modulator of the G1/S transition and prevents premature entry into S phase, genomic instability, and tumor...

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Detalles Bibliográficos
Autores principales: Cuadrado, Myriam, Garzón, Javier, Moreno, Sergio, García-Higuera, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213546/
https://www.ncbi.nlm.nih.gov/pubmed/35729193
http://dx.doi.org/10.1038/s41598-022-14331-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213546/
https://www.ncbi.nlm.nih.gov/pubmed/35729193
http://dx.doi.org/10.1038/s41598-022-14331-6

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