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NANOG initiates epiblast fate through the coordination of pluripotency genes expression

The epiblast is the source of all mammalian embryonic tissues and of pluripotent embryonic stem cells. It differentiates alongside the primitive endoderm in a “salt and pepper” pattern from inner cell mass (ICM) progenitors during the preimplantation stages through the activity of NANOG, GATA6 and t...

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Detalles Bibliográficos
Autores principales: Allègre, Nicolas, Chauveau, Sabine, Dennis, Cynthia, Renaud, Yoan, Meistermann, Dimitri, Estrella, Lorena Valverde, Pouchin, Pierre, Cohen-Tannoudji, Michel, David, Laurent, Chazaud, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213552/
https://www.ncbi.nlm.nih.gov/pubmed/35729116
http://dx.doi.org/10.1038/s41467-022-30858-8