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NANOG initiates epiblast fate through the coordination of pluripotency genes expression
The epiblast is the source of all mammalian embryonic tissues and of pluripotent embryonic stem cells. It differentiates alongside the primitive endoderm in a “salt and pepper” pattern from inner cell mass (ICM) progenitors during the preimplantation stages through the activity of NANOG, GATA6 and t...
Autores principales: | Allègre, Nicolas, Chauveau, Sabine, Dennis, Cynthia, Renaud, Yoan, Meistermann, Dimitri, Estrella, Lorena Valverde, Pouchin, Pierre, Cohen-Tannoudji, Michel, David, Laurent, Chazaud, Claire |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213552/ https://www.ncbi.nlm.nih.gov/pubmed/35729116 http://dx.doi.org/10.1038/s41467-022-30858-8 |
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