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Absence of causal association between Vitamin D and bone mineral density across the lifespan: a Mendelian randomization study

Vitamin D deficiency is a candidate risk factor for osteoporosis, characterized by decreased bone mineral density (BMD). We performed this two-sample Mendelian randomization (MR) analysis to investigate the causal effect of vitamin D on BMD. We extracted 143 single-nucleotide polymorphisms from a re...

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Detalles Bibliográficos
Autores principales: Tang, Yanchao, Wei, Feng, Yu, Miao, Zhou, Hua, Wang, Yongqiang, Cui, Zhiyong, Liu, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213555/
https://www.ncbi.nlm.nih.gov/pubmed/35729194
http://dx.doi.org/10.1038/s41598-022-14548-5