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Role of Sphingolipids in Multiple Myeloma Progression, Drug Resistance, and Their Potential as Therapeutic Targets

Multiple myeloma (MM) is an incapacitating hematological malignancy characterized by accumulation of cancerous plasma cells in the bone marrow (BM) and production of an abnormal monoclonal protein (M-protein). The BM microenvironment has a key role in myeloma development by facilitating the growth o...

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Detalles Bibliográficos
Autores principales: Petrusca, Daniela N., Lee, Kelvin P., Galson, Deborah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213658/
https://www.ncbi.nlm.nih.gov/pubmed/35756630
http://dx.doi.org/10.3389/fonc.2022.925807