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Interspecies complementation identifies a pathway to assemble SNAREs

Unc18 and SNARE proteins form the core of the membrane fusion complex at synapses. To understand the functional interactions within the core machinery, we adopted an “interspecies complementation” approach in Caenorhabditis elegans. Substitutions of individual SNAREs and Unc18 proteins with those fr...

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Detalles Bibliográficos
Autores principales: Parra-Rivas, Leonardo A., Palfreyman, Mark T., Vu, Thien N., Jorgensen, Erik M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213704/
https://www.ncbi.nlm.nih.gov/pubmed/35754735
http://dx.doi.org/10.1016/j.isci.2022.104506