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The Chromatin Landscape Channels DNA Double-Strand Breaks to Distinct Repair Pathways
DNA double-strand breaks (DSBs), the most deleterious DNA lesions, are primarily repaired by two pathways, namely homologous recombination (HR) and non-homologous end joining (NHEJ), the choice of which is largely dependent on cell cycle phase and the local chromatin landscape. Recent studies have r...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213757/ https://www.ncbi.nlm.nih.gov/pubmed/35757003 http://dx.doi.org/10.3389/fcell.2022.909696 |