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APOBEC mutagenesis is low in most types of non-B DNA structures

While somatic mutations are known to be enriched in genome regions with non-canonical DNA secondary structure, the impact of particular mutagens still needs to be elucidated. Here, we demonstrate that in human cancers, the APOBEC mutagenesis is not enriched in direct repeats, mirror repeats, short t...

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Detalles Bibliográficos
Autores principales: Ponomarev, Gennady V., Fatykhov, Bulat, Nazarov, Vladimir A., Abasov, Ruslan, Shvarov, Evgeny, Landik, Nina-Vicky, Denisova, Alexandra A., Chervova, Almira A., Gelfand, Mikhail S., Kazanov, Marat D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213766/
https://www.ncbi.nlm.nih.gov/pubmed/35754742
http://dx.doi.org/10.1016/j.isci.2022.104535