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Identification of two lipid phosphatases that regulate sphingosine-1-phosphate cellular uptake and recycling

Sphingosine-1-phosphate (S1P) is a sphingolipid metabolite that serves as a potent extracellular signaling molecule. Metabolic regulation of extracellular S1P levels impacts key cellular activities through altered S1P receptor signaling. Although the pathway through which S1P is degraded within the...

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Detalles Bibliográficos
Autores principales: Kono, Mari, Hoachlander-Hobby, Lila E., Majumder, Saurav, Schwartz, Ronit, Byrnes, Colleen, Zhu, Hongling, Proia, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213771/
https://www.ncbi.nlm.nih.gov/pubmed/35568252
http://dx.doi.org/10.1016/j.jlr.2022.100225