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Subventricular zone adult mouse neural stem cells require insulin receptor for self-renewal
The insulin receptor (INSR) is an evolutionarily conserved signaling protein that regulates development and cellular metabolism. INSR signaling promotes neurogenesis in Drosophila; however, a specific role for the INSR in maintaining adult neural stem cells (NSCs) in mammals has not been investigate...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213826/ https://www.ncbi.nlm.nih.gov/pubmed/35523180 http://dx.doi.org/10.1016/j.stemcr.2022.04.007 |