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Subventricular zone adult mouse neural stem cells require insulin receptor for self-renewal

The insulin receptor (INSR) is an evolutionarily conserved signaling protein that regulates development and cellular metabolism. INSR signaling promotes neurogenesis in Drosophila; however, a specific role for the INSR in maintaining adult neural stem cells (NSCs) in mammals has not been investigate...

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Detalles Bibliográficos
Autores principales: Chidambaram, Shravanthi, Velloso, Fernando J., Rothbard, Deborah E., Deshpande, Kaivalya, Cajuste, Yvelande, Snyder, Kristin M., Fajardo, Eduardo, Fiser, Andras, Tapinos, Nikos, Levison, Steven W., Wood, Teresa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213826/
https://www.ncbi.nlm.nih.gov/pubmed/35523180
http://dx.doi.org/10.1016/j.stemcr.2022.04.007