Iron accumulation induces oxidative stress, while depressing inflammatory polarization in human iPSC-derived microglia
Iron accumulation in microglia has been observed in Alzheimer’s disease and other neurodegenerative disorders and is thought to contribute to disease progression through various mechanisms, including neuroinflammation. To study this interaction, we treated human induced pluripotent stem cell-derived...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213827/ https://www.ncbi.nlm.nih.gov/pubmed/35523178 http://dx.doi.org/10.1016/j.stemcr.2022.04.006 |