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Iron accumulation induces oxidative stress, while depressing inflammatory polarization in human iPSC-derived microglia

Iron accumulation in microglia has been observed in Alzheimer’s disease and other neurodegenerative disorders and is thought to contribute to disease progression through various mechanisms, including neuroinflammation. To study this interaction, we treated human induced pluripotent stem cell-derived...

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Detalles Bibliográficos
Autores principales:	Kenkhuis, Boyd, van Eekeren, Michelle, Parfitt, David A., Ariyurek, Yavuz, Banerjee, Poulomi, Priller, Josef, van der Weerd, Louise, van Roon-Mom, Willeke M.C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213827/ https://www.ncbi.nlm.nih.gov/pubmed/35523178 http://dx.doi.org/10.1016/j.stemcr.2022.04.006

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