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Bioenergetic Phenotyping of DEN-Induced Hepatocellular Carcinoma Reveals a Link Between Adenylate Kinase Isoform Expression and Reduced Complex I-Supported Respiration

Hepatocellular carcinoma (HCC) is the most common form of liver cancer worldwide. Increasing evidence suggests that mitochondria play a central role in malignant metabolic reprogramming in HCC, which may promote disease progression. To comprehensively evaluate the mitochondrial phenotype present in...

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Detalles Bibliográficos
Autores principales: McLaughlin, Kelsey L., Nelson, Margaret A.M., Coalson, Hannah S., Hagen, James T., Montgomery, McLane M., Wooten, Ashley R., Zeczycki, Tonya N., Vohra, Nasreen A., Fisher-Wellman, Kelsey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213884/
https://www.ncbi.nlm.nih.gov/pubmed/35756609
http://dx.doi.org/10.3389/fonc.2022.919880