HIF1α-Dependent Induction of TFRC by a Combination of Intestinal Inflammation and Systemic Iron Deficiency in Inflammatory Bowel Disease

Background and Aims: Iron deficiency (ID) is a frequent extra-intestinal manifestation in patients with Inflammatory Bowel Disease (IBD), who often do not respond to iron supplementation. Iron is a cofactor for hydroxylases that suppress the hypoxia-inducible factor-1α (HIF1α), a transcription facto...

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Detalles Bibliográficos
Autores principales: Fagundes, Raphael R., Bourgonje, Arno R., Hu, Shixian, Barbieri, Ruggero, Jansen, Bernadien H., Sinnema, Nienke, Blokzijl, Tjasso, Taylor, Cormac T., Weersma, Rinse K., Faber, Klaas Nico, Dijkstra, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214203/
https://www.ncbi.nlm.nih.gov/pubmed/35755436
http://dx.doi.org/10.3389/fphys.2022.889091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214203/
https://www.ncbi.nlm.nih.gov/pubmed/35755436
http://dx.doi.org/10.3389/fphys.2022.889091

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