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Signal Recognition Particle in Human Diseases

The signal recognition particle (SRP) is a ribonucleoprotein complex with dual functions. It co-translationally targets proteins with a signal sequence to the endoplasmic reticulum (ER) and protects their mRNA from degradation. If SRP is depleted or cannot recognize the signal sequence, then the Reg...

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Detalles Bibliográficos
Autores principales: Kellogg, Morgana K., Tikhonova, Elena B., Karamyshev, Andrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214365/
https://www.ncbi.nlm.nih.gov/pubmed/35754847
http://dx.doi.org/10.3389/fgene.2022.898083