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Signal Recognition Particle in Human Diseases
The signal recognition particle (SRP) is a ribonucleoprotein complex with dual functions. It co-translationally targets proteins with a signal sequence to the endoplasmic reticulum (ER) and protects their mRNA from degradation. If SRP is depleted or cannot recognize the signal sequence, then the Reg...
Autores principales: | Kellogg, Morgana K., Tikhonova, Elena B., Karamyshev, Andrey L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214365/ https://www.ncbi.nlm.nih.gov/pubmed/35754847 http://dx.doi.org/10.3389/fgene.2022.898083 |
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