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Hederacoside C ameliorates colitis via restoring impaired intestinal barrier through moderating S100A9/MAPK and neutrophil recruitment inactivation

Hederacoside C (HSC) has attracted much attention as a novel modulator of inflammation, but its anti-inflammatory mechanism remains elusive. In the present study, we investigated how HSC attenuated intestinal inflammation in vivo and in vitro. HSC injection significantly alleviated TNBS-induced coli...

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Detalles Bibliográficos
Autores principales: Zha, Zheng-xia, Lin, Yu, Wang, Ke-xin, Zhang, Yan-lin, Li, Dan, Xu, Guo-qiang, Xu, Qiong-ming, Liu, Yan-li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214479/
https://www.ncbi.nlm.nih.gov/pubmed/35732707
http://dx.doi.org/10.1038/s41401-022-00933-3