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Proteo-genetic analysis reveals clear hierarchy of ESX-1 secretion in Mycobacterium marinum
The ESX-1 (ESAT-6-system-1) system and the protein substrates it transports are essential for mycobacterial pathogenesis. The precise ways that ESX-1 substrates contribute to virulence remains unknown. Several known ESX-1 substrates are also required for the secretion of other proteins. We used a pr...
Autores principales: | Cronin, Rachel M., Ferrell, Micah J., Cahir, Clare W., Champion, Matthew M., Champion, Patricia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214503/ https://www.ncbi.nlm.nih.gov/pubmed/35671426 http://dx.doi.org/10.1073/pnas.2123100119 |
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