Intranasal inoculation of an MVA-based vaccine induces IgA and protects the respiratory tract of hACE2 mice from SARS-CoV-2 infection

Current vaccines have greatly diminished the severity of the COVID-19 pandemic, even though they do not entirely prevent infection and transmission, likely due to insufficient immunity in the upper respiratory tract. Here, we compare intramuscular and intranasal administration of a live, replication...

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Detalles Bibliográficos
Autores principales: Americo, Jeffrey L., Cotter, Catherine A., Earl, Patricia L., Liu, Ruikang, Moss, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214525/
https://www.ncbi.nlm.nih.gov/pubmed/35679343
http://dx.doi.org/10.1073/pnas.2202069119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214525/
https://www.ncbi.nlm.nih.gov/pubmed/35679343
http://dx.doi.org/10.1073/pnas.2202069119

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