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Intranasal inoculation of an MVA-based vaccine induces IgA and protects the respiratory tract of hACE2 mice from SARS-CoV-2 infection
Current vaccines have greatly diminished the severity of the COVID-19 pandemic, even though they do not entirely prevent infection and transmission, likely due to insufficient immunity in the upper respiratory tract. Here, we compare intramuscular and intranasal administration of a live, replication...
Autores principales: | Americo, Jeffrey L., Cotter, Catherine A., Earl, Patricia L., Liu, Ruikang, Moss, Bernard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214525/ https://www.ncbi.nlm.nih.gov/pubmed/35679343 http://dx.doi.org/10.1073/pnas.2202069119 |
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