ZBP1 promotes inflammatory responses downstream of TLR3/TLR4 via timely delivery of RIPK1 to TRIF

ZBP1 is widely recognized as a mediator of cell death for its role in initiating necroptotic, apoptotic, and pyroptotic cell death pathways in response to diverse pathogenic infection. Herein, we characterize an unanticipated role for ZBP1 in promoting inflammatory responses to bacterial lipopolysac...

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Detalles Bibliográficos
Autores principales: Muendlein, Hayley I., Connolly, Wilson M., Magri, Zoie, Jetton, David, Smirnova, Irina, Degterev, Alexei, Balachandran, Siddharth, Poltorak, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214535/
https://www.ncbi.nlm.nih.gov/pubmed/35666872
http://dx.doi.org/10.1073/pnas.2113872119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214535/
https://www.ncbi.nlm.nih.gov/pubmed/35666872
http://dx.doi.org/10.1073/pnas.2113872119

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