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ZBP1 promotes inflammatory responses downstream of TLR3/TLR4 via timely delivery of RIPK1 to TRIF
ZBP1 is widely recognized as a mediator of cell death for its role in initiating necroptotic, apoptotic, and pyroptotic cell death pathways in response to diverse pathogenic infection. Herein, we characterize an unanticipated role for ZBP1 in promoting inflammatory responses to bacterial lipopolysac...
Autores principales: | Muendlein, Hayley I., Connolly, Wilson M., Magri, Zoie, Jetton, David, Smirnova, Irina, Degterev, Alexei, Balachandran, Siddharth, Poltorak, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214535/ https://www.ncbi.nlm.nih.gov/pubmed/35666872 http://dx.doi.org/10.1073/pnas.2113872119 |
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