The M(1) muscarinic receptor is present in situ as a ligand-regulated mixture of monomers and oligomeric complexes

The quaternary organization of rhodopsin-like G protein-coupled receptors in native tissues is unknown. To address this we generated mice in which the M(1) muscarinic acetylcholine receptor was replaced with a C-terminally monomeric enhanced green fluorescent protein (mEGFP)–linked variant. Fluoresc...

Descripción completa

Detalles Bibliográficos
Autores principales: Marsango, Sara, Jenkins, Laura, Pediani, John D., Bradley, Sophie J., Ward, Richard J., Hesse, Sarah, Biener, Gabriel, Stoneman, Michael R., Tobin, Andrew B., Raicu, Valerica, Milligan, Graeme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214538/
https://www.ncbi.nlm.nih.gov/pubmed/35671422
http://dx.doi.org/10.1073/pnas.2201103119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214538/
https://www.ncbi.nlm.nih.gov/pubmed/35671422
http://dx.doi.org/10.1073/pnas.2201103119

Ejemplares similares