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WNT/RYK signaling functions as an antiinflammatory modulator in the lung mesenchyme

A number of inflammatory lung diseases, including chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, and pneumonia, are modulated by WNT/β-catenin signaling. However, the underlying molecular mechanisms remain unclear. Here, starting with a forward genetic screen in mouse, we iden...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Taek, Panza, Paolo, Kikhi, Khrievono, Nakamichi, Yuko, Atzberger, Ann, Guenther, Stefan, Ruppert, Clemens, Guenther, Andreas, Stainier, Didier Y. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214544/
https://www.ncbi.nlm.nih.gov/pubmed/35671428
http://dx.doi.org/10.1073/pnas.2201707119