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Screening membraneless organelle participants with machine-learning models that integrate multimodal features

Protein self-assembly is one of the formation mechanisms of biomolecular condensates. However, most phase-separating systems (PS) demand multiple partners in biological conditions. In this study, we divided PS proteins into two groups according to the mechanism by which they undergo PS: PS-Self prot...

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Detalles Bibliográficos
Autores principales: Chen, Zhaoming, Hou, Chao, Wang, Liang, Yu, Chunyu, Chen, Taoyu, Shen, Boyan, Hou, Yaoyao, Li, Pilong, Li, Tingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214545/
https://www.ncbi.nlm.nih.gov/pubmed/35687670
http://dx.doi.org/10.1073/pnas.2115369119