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Ketamine administration ameliorates anesthesia and surgery-induced cognitive dysfunction via activation of TRPV4 channel opening

Perioperative neurocognitive disorder (PND) is a common complication associated with anesthesia and surgery in the elderly. The dysfunction of transient receptor potential vanilloid 4 (TRPV4) has been associated with a number of diseases, including Alzheimer's disease. Given that ketamine can r...

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Detalles Bibliográficos
Autores principales: Li, Qi, Zhou, Dong-Na, Tu, Yi-Qing, Wu, Xin-Wei, Pei, Da-Qing, Xiong, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214599/
https://www.ncbi.nlm.nih.gov/pubmed/35761804
http://dx.doi.org/10.3892/etm.2022.11405