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TLR4 Modulates Senescence and Paracrine Action in Placental Mesenchymal Stem Cells via Inhibiting Hedgehog Signaling Pathway in Preeclampsia

Preeclampsia (PE) is a heterogeneous disease closely associated with the accelerated senescence of the placentas. Placental mesenchymal stem cells (PMSCs) modulate placental development, which is abnormally senescent in PE together with abnormal paracrine. Both pivotal in the placenta development, T...

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Detalles Bibliográficos
Autores principales: Zhong, Yanqi, Zhang, Yang, Liu, Weifang, Zhao, Yin, Zou, Li, Liu, Xiaoxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214654/
https://www.ncbi.nlm.nih.gov/pubmed/35757501
http://dx.doi.org/10.1155/2022/7202837