Cargando…

TLR4 Modulates Senescence and Paracrine Action in Placental Mesenchymal Stem Cells via Inhibiting Hedgehog Signaling Pathway in Preeclampsia

Preeclampsia (PE) is a heterogeneous disease closely associated with the accelerated senescence of the placentas. Placental mesenchymal stem cells (PMSCs) modulate placental development, which is abnormally senescent in PE together with abnormal paracrine. Both pivotal in the placenta development, T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhong, Yanqi, Zhang, Yang, Liu, Weifang, Zhao, Yin, Zou, Li, Liu, Xiaoxia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214654/ https://www.ncbi.nlm.nih.gov/pubmed/35757501 http://dx.doi.org/10.1155/2022/7202837

Ejemplares similares

Significance of Placental Mesenchymal Stem Cell in Placenta Development and Implications for Preeclampsia
por: Zhang, Yang, et al.
Publicado: (2022)

Metformin Corrects Glucose Metabolism Reprogramming and NLRP3 Inflammasome-Induced Pyroptosis via Inhibiting the TLR4/NF-κB/PFKFB3 Signaling in Trophoblasts: Implication for a Potential Therapy of Preeclampsia
por: Zhang, Yang, et al.
Publicado: (2021)

PFKFB3-mediated glycometabolism reprogramming modulates endothelial differentiation and angiogenic capacity of placenta-derived mesenchymal stem cells
por: Zhang, Yang, et al.
Publicado: (2022)

Paracrine Senescence of Mesenchymal Stromal Cells Involves Inflammatory Cytokines and the NF-κB Pathway
por: Chou, Lun-Yin, et al.
Publicado: (2022)

Doxorubicin induces an alarmin-like TLR4-dependent autocrine/paracrine action of Nucleophosmin in human cardiac mesenchymal progenitor cells
por: Beji, Sara, et al.
Publicado: (2021)

Paracrine effects of TLR4-polarised mesenchymal stromal cells are mediated by extracellular vesicles
por: Zeuner, Marie-Theres, et al.
Publicado: (2016)

Placental Aromatase Is Deficient in Placental Ischemia and Preeclampsia
por: Perez-Sepulveda, Alejandra, et al.
Publicado: (2015)

Human placental mesenchymal stromal cells are ciliated and their ciliation is compromised in preeclampsia
por: Romberg, Sophia Indira, et al.
Publicado: (2022)

Protein Profiling of Preeclampsia Placental Tissues
por: Shu, Chang, et al.
Publicado: (2014)

RNAi Modulation of Placental sFLT1 for the Treatment of Preeclampsia.
por: Turanov, Anton A., et al.
Publicado: (2018)

Placental Mitochondrial Abnormalities in Preeclampsia
por: Vangrieken, Philippe, et al.
Publicado: (2021)

Paracrine roles of cellular senescence in promoting tumourigenesis
por: Gonzalez-Meljem, Jose Mario, et al.
Publicado: (2018)

The Downregulation of Placental Lumican Promotes the Progression of Preeclampsia
por: Liu, Chao, et al.
Publicado: (2021)

Placenta-Targeted Nanoparticles Loaded with PFKFB3 Overexpression Plasmids Enhance Angiogenesis and Placental Function
por: Li, Qi, et al.
Publicado: (2022)

Mesenchymal stem cell senescence alleviates their intrinsic and seno-suppressive paracrine properties contributing to osteoarthritis development
por: Malaise, Olivier, et al.
Publicado: (2019)

Paracrine sonic hedgehog signalling by prostate cancer cells induces osteoblast differentiation
por: Zunich, Samantha M, et al.
Publicado: (2009)

Oxidative Stress in Preeclampsia and Placental Diseases
por: Aouache, Rajaa, et al.
Publicado: (2018)

Disruption of Placental Homeostasis Leads to Preeclampsia
por: Nakashima, Akitoshi, et al.
Publicado: (2020)

Placental Mitochondrial Function and Dysfunction in Preeclampsia
por: Jahan, Fahmida, et al.
Publicado: (2023)

Unique Clinical and Histological Features of Placental Mesenchymal Dysplasia Complicated by Severe Preeclampsia in the Midtrimester
por: Kuwabara, Yoshimitsu, et al.
Publicado: (2020)

Paracrine Action of Mesenchymal Stem Cells Revealed by Single Cell Gene Profiling in Infarcted Murine Hearts
por: Yao, Yan, et al.
Publicado: (2015)

Trophoblast-Targeted Nanomedicine Modulates Placental sFLT1 for Preeclampsia Treatment
por: Li, Lei, et al.
Publicado: (2020)

Paracrine and endocrine modes of myostatin action
por: Lee, Yun-Sil, et al.
Publicado: (2016)

MALAT1 sponges miR-26a and miR-26b to regulate endothelial cell angiogenesis via PFKFB3-driven glycolysis in early-onset preeclampsia
por: Li, Qi, et al.
Publicado: (2021)

Pro-Inflammatory Profile of Preeclamptic Placental Mesenchymal Stromal Cells: New Insights into the Etiopathogenesis of Preeclampsia
por: Rolfo, Alessandro, et al.
Publicado: (2013)

Role of the Placental Vitamin D Receptor in Modulating Feto-Placental Growth in Fetal Growth Restriction and Preeclampsia-Affected Pregnancies
por: Murthi, Padma, et al.
Publicado: (2016)

Paracrine cellular senescence exacerbates biliary injury and impairs regeneration
por: Ferreira-Gonzalez, Sofia, et al.
Publicado: (2018)

Paracrine and endocrine actions of bone—the functions of secretory proteins from osteoblasts, osteocytes, and osteoclasts
por: Han, Yujiao, et al.
Publicado: (2018)

Placental Peripartum Pathologies in Women with Preeclampsia and Eclampsia
por: Ezeigwe, Chijioke Ogomegbulam, et al.
Publicado: (2018)

The Role of Epigenetics in Placental Development and the Etiology of Preeclampsia
por: Apicella, Clara, et al.
Publicado: (2019)

Purinergic and muscarinic modulation of ATP release from the urothelium and its paracrine actions
por: Sui, Guiping, et al.
Publicado: (2013)

Paracrine effects of human adipose-derived mesenchymal stem cells in inflammatory stress-induced senescence features of osteoarthritic chondrocytes
por: Platas, Julia, et al.
Publicado: (2016)

Radiation-Induced Osteocyte Senescence Alters Bone Marrow Mesenchymal Stem Cell Differentiation Potential via Paracrine Signaling
por: Xu, Linshan, et al.
Publicado: (2021)

The Placental Innate Immune System Is Altered in Early-Onset Preeclampsia, but Not in Late-Onset Preeclampsia
por: Broekhuizen, Michelle, et al.
Publicado: (2021)

Adiponectin Action: A Combination of Endocrine and Autocrine/Paracrine Effects
por: Dadson, Keith, et al.
Publicado: (2011)

The Local Paracrine Actions of the Pancreatic α-Cell
por: Rodriguez-Diaz, Rayner, et al.
Publicado: (2020)

Sonic Hedgehog Induces Mesenchymal Stromal Cell Senescence-Associated Secretory Phenotype and Chondrocyte Apoptosis in Human Osteoarthritic Cartilage
por: Feng, Meng, et al.
Publicado: (2021)

A complex secretory program orchestrated by the inflammasome controls paracrine senescence
por: Acosta, Juan Carlos, et al.
Publicado: (2013)

Adamantinomatous craniopharyngioma as a model to understand paracrine and senescence-induced tumourigenesis
por: Gonzalez-Meljem, Jose Mario, et al.
Publicado: (2021)

Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner
por: Lagnado, Anthony, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ghb652vms9j3vv4j99rglkvvi7