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Role of the cGAS–STING pathway in systemic and organ-specific diseases

Cells are equipped with numerous sensors that recognize nucleic acids, which probably evolved for defence against viruses. Once triggered, these sensors stimulate the production of type I interferons and other cytokines that activate immune cells and promote an antiviral state. The evolutionary cons...

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Detalles Bibliográficos
Autores principales: Skopelja-Gardner, Sladjana, An, Jie, Elkon, Keith B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214686/
https://www.ncbi.nlm.nih.gov/pubmed/35732833
http://dx.doi.org/10.1038/s41581-022-00589-6