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Role of the cGAS–STING pathway in systemic and organ-specific diseases
Cells are equipped with numerous sensors that recognize nucleic acids, which probably evolved for defence against viruses. Once triggered, these sensors stimulate the production of type I interferons and other cytokines that activate immune cells and promote an antiviral state. The evolutionary cons...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214686/ https://www.ncbi.nlm.nih.gov/pubmed/35732833 http://dx.doi.org/10.1038/s41581-022-00589-6 |