Palmitate induces DNA damage and senescence in human adipocytes in vitro that can be alleviated by oleic acid but not inorganic nitrate

Hypertrophy in white adipose tissue (WAT) can result in sustained systemic inflammation, hyperlipidaemia, insulin resistance, and onset of senescence in adipocytes. Inflammation and hypertrophy can be induced in vitro using palmitic acid (PA). WAT adipocytes have innately low β-oxidation capacity, w...

Descripción completa

Detalles Bibliográficos
Autores principales: Ishaq, Abbas, Tchkonia, Tamara, Kirkland, James L., Siervo, Mario, Saretzki, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214712/
https://www.ncbi.nlm.nih.gov/pubmed/35390489
http://dx.doi.org/10.1016/j.exger.2022.111798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214712/
https://www.ncbi.nlm.nih.gov/pubmed/35390489
http://dx.doi.org/10.1016/j.exger.2022.111798

Ejemplares similares