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Repurposing of intestinal defensins as multi-target, dual-function amyloid inhibitors via cross-seeding

Amyloid formation and microbial infection are the two common pathological causes of neurogenerative diseases, including Alzheimer's disease (AD), type II diabetes (T2D), and medullary thyroid carcinoma (MTC). While significant efforts have been made to develop different prevention strategies an...

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Detalles Bibliográficos
Autores principales: Tang, Yijing, Zhang, Dong, Gong, Xiong, Zheng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214849/
https://www.ncbi.nlm.nih.gov/pubmed/35799805
http://dx.doi.org/10.1039/d2sc01447e