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N-glycosylation stabilizes MerTK and promotes hepatocellular carcinoma tumor growth

Despite the evidences of elevated expression of Mer tyrosine kinase (MerTK) in multiple human cancers, mechanisms underlying the oncogenic roles of MerTK in hepatocellular carcinoma (HCC) remains undefined. We explored the functional effects of MerTK and N-Glycosylated MerTK on HCC cell survival and...

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Detalles Bibliográficos
Autores principales: Liu, Yongzhang, Lan, Linhua, Li, Yujie, Lu, Jing, He, Lipeng, Deng, Yao, Fei, Mingming, Lu, Jun-Wan, Shangguan, Fugen, Lu, Ju-Ping, Wang, Jiaxin, Wu, Liang, Huang, Kate, Lu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214875/
https://www.ncbi.nlm.nih.gov/pubmed/35728303
http://dx.doi.org/10.1016/j.redox.2022.102366