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RResolver: efficient short-read repeat resolution within ABySS

BACKGROUND: De novo genome assembly is essential to modern genomics studies. As it is not biased by a reference, it is also a useful method for studying genomes with high variation, such as cancer genomes. De novo short-read assemblers commonly use de Bruijn graphs, where nodes are sequences of equa...

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Detalles Bibliográficos
Autores principales: Nikolić, Vladimir, Afshinfard, Amirhossein, Chu, Justin, Wong, Johnathan, Coombe, Lauren, Nip, Ka Ming, Warren, René L., Birol, Inanç
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215042/
https://www.ncbi.nlm.nih.gov/pubmed/35729491
http://dx.doi.org/10.1186/s12859-022-04790-z