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Positive interaction between GPER and β-alanine in the dorsal root ganglion uncovers potential mechanisms: mediating continuous neuronal sensitization and neuroinflammation responses in neuropathic pain

BACKGROUND: The pathogenesis of neuropathic pain and the reasons for the prolonged unhealing remain unknown. Increasing evidence suggests that sex oestrogen differences play a role in pain sensitivity, but few studies have focused on the oestrogen receptor which may be an important molecular compone...

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Detalles Bibliográficos
Autores principales: Xu, Zhenzhen, Xie, Wanli, Feng, Yiqi, Wang, Yanting, Li, Xia, Liu, Jie, Xiong, Yue, He, Yuyao, Chen, Lu, Liu, Guoyang, Wu, Qingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215054/
https://www.ncbi.nlm.nih.gov/pubmed/35729568
http://dx.doi.org/10.1186/s12974-022-02524-9