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An acetyltransferase controls the metabolic flux in rubromycin polyketide biosynthesis by direct modulation of redox tailoring enzymes

The often complex control of bacterial natural product biosynthesis typically involves global and pathway-specific transcriptional regulators of gene expression, which often limits the yield of bioactive compounds under laboratory conditions. However, little is known about regulation mechanisms on t...

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Detalles Bibliográficos
Autores principales: Toplak, Marina, Nagel, Adelheid, Frensch, Britta, Lechtenberg, Thorsten, Teufel, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215129/
https://www.ncbi.nlm.nih.gov/pubmed/35799824
http://dx.doi.org/10.1039/d2sc01952c