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Efficacy and limitations of senolysis in atherosclerosis

AIMS: Traditional markers of cell senescence including p16, Lamin B1, and senescence-associated beta galactosidase (SAβG) suggest very high frequencies of senescent cells in atherosclerosis, while their removal via ‘senolysis’ has been reported to reduce atherogenesis. However, selective killing of...

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Detalles Bibliográficos
Autores principales: Garrido, Abel Martin, Kaistha, Anuradha, Uryga, Anna K, Oc, Sebnem, Foote, Kirsty, Shah, Aarti, Finigan, Alison, Figg, Nichola, Dobnikar, Lina, Jørgensen, Helle, Bennett, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215197/
https://www.ncbi.nlm.nih.gov/pubmed/34142149
http://dx.doi.org/10.1093/cvr/cvab208