Epigenetic regulation of EIF4A1 through DNA methylation and an oncogenic role of eIF4A1 through BRD2 signaling in prostate cancer

In prostate cancers, elongation initiation factor 4A1 (eIF4A1) supports an oncogenic translation program and is highly expressed, but its role remains elusive. By use of human specimens and cell models, we addressed the role of eIF4A1 in prostate cancer in vitro and in vivo. EIF4A1 expression, as de...

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Detalles Bibliográficos
Autores principales: Wang, Chao, Leavenworth, Jonathan, Zhang, Chao, Liu, Zhichao, Yuan, Katherine Y., Wang, Yichun, Zhang, Guangxin, Wang, Shuaibin, Cui, Xuelian, Zhang, Yue, Bae, Sejong, Zhou, Jiangbing, Wang, Lizhong, Liu, Runhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215223/
https://www.ncbi.nlm.nih.gov/pubmed/35361883
http://dx.doi.org/10.1038/s41388-022-02272-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215223/
https://www.ncbi.nlm.nih.gov/pubmed/35361883
http://dx.doi.org/10.1038/s41388-022-02272-3

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