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SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication

SARS-CoV-2 is the causative agent of the ongoing pandemic of coronavirus disease 2019 (COVID-19) and poses a significant threat to global health. N protein (NP), which is a major pathogenic protein among betacoronaviruses, binds to the viral RNA genome to allow viral genome packaging and viral parti...

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Detalles Bibliográficos
Autores principales: Liu, Hainan, Bai, Yu, Zhang, Xun, Gao, Ting, Liu, Yue, Li, Entao, Wang, Xuefeng, Cao, Zheng, Zhu, Lin, Dong, Qincai, Hu, Yong, Wang, Guangfei, Song, Caiwei, Niu, Xiayang, Zheng, Tong, Wang, Di, Liu, Zijing, Jin, Yanwen, Li, Ping, Bian, Xiuwu, Cao, Cheng, Liu, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215227/
https://www.ncbi.nlm.nih.gov/pubmed/35652658
http://dx.doi.org/10.1128/jvi.00412-22