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Redox-sensitive E2 Rad6 controls cellular response to oxidative stress via K63-linked ubiquitination of ribosomes

Protein ubiquitination is an essential process that rapidly regulates protein synthesis, function, and fate in dynamic environments. Within its non-proteolytic functions, we showed that K63-linked polyubiquitinated conjugates heavily accumulate in yeast cells exposed to oxidative stress, stalling ri...

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Detalles Bibliográficos
Autores principales: Simões, Vanessa, Cizubu, Blanche K., Harley, Lana, Zhou, Ye, Pajak, Joshua, Snyder, Nathan A., Bouvette, Jonathan, Borgnia, Mario J., Arya, Gaurav, Bartesaghi, Alberto, Silva, Gustavo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215706/
https://www.ncbi.nlm.nih.gov/pubmed/35613580
http://dx.doi.org/10.1016/j.celrep.2022.110860