Macrophage-derived secretome is sufficient to confer olanzapine-mediated insulin resistance in human adipocytes

OBJECTIVE: Olanzapine and Aripiprazole are widely used second-generation antipsychotic drugs. Olanzapine, more than Aripiprazole, leads to considerable metabolic side effects including obesity and diabetes. While the underlying mechanisms are not fully understood, these side effects are likely assoc...

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Detalles Bibliográficos
Autores principales: Dipta, Priya, Sarsenbayeva, Assel, Shmuel, Miriam, Forno, Francesca, Eriksson, Jan W., Pereira, Maria J., Abalo, Xesús M., Wabitsch, Martin, Thaysen-Andersen, Morten, Tirosh, Boaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Preclinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216267/
https://www.ncbi.nlm.nih.gov/pubmed/35757056
http://dx.doi.org/10.1016/j.cpnec.2021.100073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216267/
https://www.ncbi.nlm.nih.gov/pubmed/35757056
http://dx.doi.org/10.1016/j.cpnec.2021.100073

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