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Inhibition of glucocorticoid synthesis alleviates cognitive impairment in high-fat diet-induced obese mice

In addition to cardiovascular diseases, metabolic syndrome and type 2 diabetes mellitus, obesity is associated with cognitive deficits. In rodents, it has been shown that long-term high-fat diet (HFD) consumption leads to the alteration of hypothalamic-pituitary-adrenal (HPA) axis resulting in incre...

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Detalles Bibliográficos
Autores principales: Janthakhin, Yoottana, Kingtong, Sutin, Juntapremjit, Sirikran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216272/
https://www.ncbi.nlm.nih.gov/pubmed/35755209
http://dx.doi.org/10.1016/j.cpnec.2022.100130