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Quercetin and luteolin are single-digit micromolar inhibitors of the SARS-CoV-2 RNA-dependent RNA polymerase

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly become a global health pandemic. Among the viral proteins, RNA-dependent RNA polymerase (RdRp) is responsible for viral genome replication and has emerged as one of the most promising targets for pharmacological intervention ag...

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Detalles Bibliográficos
Autores principales: Munafò, Federico, Donati, Elisa, Brindani, Nicoletta, Ottonello, Giuliana, Armirotti, Andrea, De Vivo, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216299/
https://www.ncbi.nlm.nih.gov/pubmed/35732785
http://dx.doi.org/10.1038/s41598-022-14664-2